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Expeditious Synthesis of Trifluoromethylated Heterocycles: Noncatalytic 1,3-Dipolar Cyclization of Azomethine Imines with (alpha-Trifluoromethyl)acrylates

  作者 OGAWA SHINICHI; NISHIMINE TAKAYUKI; TOKUNAGA ETSUKO; SHIBATA NORIO  
  选自 期刊  Synthesis;  卷期  2010年-19;  页码  3274-3281  
  关联知识点  
 

[摘要]A convenient, simple, and expeditious procedure for the preparation of novel trifluoromethylated bicyclic pyrazolidinone systems by noncatalytic 1,3-dipolar cyclization of azomethine imines with tert-butyl 2-(trifluoromethyl)prop-2-enoate is presented.

 
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