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A Practical Synthesis of 1,2-Nitroamines by Michael Addition of N-Nucleophiles to Nitroalkenes

  作者 ROBIETTE RAPHAEL; TRAN TRIEUVAN; CORDI ALEX; TINANT BERNARD; MARCHANDBRYNAERT JACQUELINE  
  选自 期刊  Synthesis;  卷期  2010年-18;  页码  3138-3142  
  关联知识点  
 

[摘要]A practical method for the synthesis of alpha-nitroamines by Michael addition of azide to nitroalkene has been developed. This reaction proceeds in high yields under very mild conditions (phase-transfer catalysis) and is found to be general; good yields are obtained with both aryl and alkyl derivatives as well as with 1,1-disubstituted ones.

 
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