NOVEL SYNTHESIS OF 2-ALKOXY(ARALKOXY)-5-CHLORO[1,2,4]TRIAZOLO[1,5-a]QUINAZOLINES AND THEIR DERIVATIVES

[摘要]：2-Alkoxy(aralkoxy)-5-chloro[1,2,4]triazolo[1,5-a]quinazolines have been synthesized. The corresponding 2-alkoxy(aralkoxy)[1,2,4]triazolo[1,5-a]quinazolin-5-ones were chlorinated with either oxalyl chloride or phosphorus oxychloride. The chlorine atom at 5-position of the targeted [1,2,4]triazolo[1,5-a]quinazolines was replaced with multifunctional N-nucleophiles. This provided the preparation of the heterocyclic system bearing a variety of substituents at 5-position.

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