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Structural Basis for Activation of Class Ib Ribonucleotide Reductase

  作者 Boal, AK; Cotruvo, JA; Stubbe, J; Rosenzweig, AC  
  选自 期刊  Science;  卷期  2010年329-5998;  页码  1526-1530  
  关联知识点  
 

[摘要]The class Ib ribonucleotide reductase of Escherichia coli can initiate reduction of nucleotides to deoxynucleotides with either a Mn-2(III)-tyrosyl radical (Y center dot) or a Fe-2(III)-Y center dot cofactor in the NrdF subunit. Whereas Fe-2(III)-Y center

 
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