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Broad and Potent Neutralizing Antibodies from an African Donor Reveal a New HIV-1 Vaccine Target

作者	Walker, LM; Phogat, SK; Chan-Hui, PY; Wagner, D; Phung, P; Goss, JL; Wrin, T; Simek, MD; Fling, S; Mitcham, JL; Lehrman, JK; Priddy, FH; Olsen, OA; Frey, SM; Hammond, PW; Kaminsky, S; Zamb, T; Moyle, M; Koff, WC; Poignard, P; Burton, DR

选自	期刊 Science; 卷期 2009年326-5950; 页码 285-289

关联知识点

[摘要]：Broadly neutralizing antibodies (bNAbs), which develop over time in some HIV-1-infected individuals, define critical epitopes for HIV vaccine design. Using a systematic approach, we have examined neutralization breadth in the sera of about 1800 HIV-1-infe
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