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Crystal Structure of a Nucleocapsid-Like Nucleoprotein-RNA Complex of Respiratory Syncytial Virus

  作者 Tawar, RG; Duquerroy, S; Vonrhein, C; Varela, PF; Damier-Piolle, L; Castagne, N; MacLellan, K; Bedouelle, H; Bricogne, G; Bhella, D; Eleouet, JF; Rey, FA  
  选自 期刊  Science;  卷期  2009年326-5957;  页码  1279-1283  
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[摘要]The respiratory syncytial virus (RSV) is an important human pathogen, yet neither a vaccine nor effective therapies are available to treat infection. To help elucidate the replication mechanism of this RNA virus, we determined the three-dimensional (3D) c

 
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