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gamma-Lactones and ent-Eudesmane Sesquiterpenes from the Endophytic Fungus Eutypella sp BCC 13199

  作者 Isaka, M; Palasarn, S; Lapanun, S; Chanthaket, R; Boonyuen, N; Lumyong, S  
  选自 期刊  Journal of natural products;  卷期  2009年72-9;  页码  1720-1722  
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[摘要]Two new gamma-lactones, eutypellins A (1) and B (2), and two ent-eudesmane sesquiterpenes, ent-4(15)-eudesmen-1 1-ol-1-one (3) and ent-4(15)-eudesmen-1 alpha,11-diol (4), together with three known pimarane diterpenes, diaporthein B, scopararane A, and libertellenone C, were isolated from the endophytic fungus Eutypella sp. BCC 13199. The structures of these compounds were elucidated by interpretation of spectroscopic data. The absolute configuration of 4 was confirmed by application of the modified Mosher's method. Eutypellin A (1) and sesquiterpene 3 exhibited weak cytotoxic activities.

 
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