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Cyanolide A, a Glycosidic Macrolide with Potent Molluscicidal Activity from the Papua New Guinea Cyanobacterium Lyngbya bouillonii

  作者 Pereira, AR; Mccue, CF; Gerwick, WH  
  选自 期刊  Journal of natural products;  卷期  2010年73-2;  页码  217-220  
  关联知识点  
 

[摘要]Over the last 50 years, molluscicides have played a critical role in the control of schistosomiasis transmission. Cyanolide A (2), isolated front extracts of a Papua New Guinea collection of Lyngbya bouillonii, is it new and highly potent molluscicidal agent against the snail vector Biomphalaria glabrata (LC50 = 1.2 mu M). The Structure of cyanolide A (2) was elucidated through extensive NMR spectroscopic analyses, yielding,I symmetrical dirtier that represents the newest addition to the family of glycosidic macrolides from cyanobacteria.

 
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