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Aromatic Cyclic Peroxides and Related Keto-Compounds from the Plakortis sp Component of a Sponge Consortium

  作者 Manzo, E; Ciavatta, ML; Melck, D; Schupp, P; de Voogd, N; Gavagnin, M  
  选自 期刊  Journal of natural products;  卷期  2009年72-8;  页码  1547-1551  
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[摘要]Six unreported aromatic compounds, 1-6, were isolated, along with the known compounds dehydrocurcuphenol and manoalide, from a sample of Plakortis sp., which was the main component of a Pacific sponge consortium. The new molecules were chemically characterized by spectroscopic methods. Compounds 1-4 contain a six-membered cyclic peroxide, whereas 5 and 6 display a terminal methyl ketone. The new metabolites were tested for antifungal and antibacterial properties. Compounds I and 4 were weakly active against S. aureus.

 
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