Facile Synthesis of Fluorinated 1-Desazapurines

[摘要]：A preparative approach towards 1-desazapurines, starting from 4(5)-aminoimidazoles and polyfluoroalkyl-containing 1,3-CCC-biselectrophiles was developed. As a result, a set Of fluorinated I -desazapurines was synthesized. Additionally, a synthetic route to 1-desazapurines hearing a sugar-mimicking group is proposed.

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