A Short Synthesis of Enantiomeric Phytoprostanes B-1 Type I

[摘要]：The synthesis of both enantiomers of phytoprostane B, type I from 3-[(dimethoxyphosphoryl)methyl]cyclopent-2-enone is reported. It consists of three steps including regioselective alkylation of the Substrate at C(2) with methyl 8-bromooctanoate, subsequent Horner reaction with enantiomeric O-benzoyl-protected alpha-hydroxybutanals and final methanolysis. This affords the product in 25% overall yield.

[全文传递流程]：

一般上传文献全文的时限在1个工作日内