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Facile and Efficient Synthesis of a New Class of Indole-Substituted Pyridine Derivatives via One-Pot Multicomponent Reactions

  作者 ZHAO KAI; XU XIAOPING; ZHU SONGLEI; SHI DAQING; ZHANG YONG; JI SHUNJUN  
  选自 期刊  Synthesis;  卷期  2009年-16;  页码  2697-2708  
  关联知识点  
 

[摘要]A new series of indole-containing pyridine derivatives, 4-aryl-6-(1H-indol-3-yl)-2,2'-bipyridine-5-carbonitriles, were synthesized via one-pot multicomponent reactions of 3-(cyanoacetyl)indoles, aldehydes, heterocyclic ketones, and ammonium acetate. Particularly valuable features of this method include high yields of products, broad substrate scope, and straightforward procedures.

 
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