Synthesis of 2-Amino-3,4-dihydroquinazolines and Imidazo[2,1-b]quinazoline-2-ones

[摘要]：A straightforward method for the synthesis of 2-amino-3,4-dihydroquinazolines from Baylis-Hillman derivatives is disclosed. The protocol involves sequential S(N)2 reaction of a primary airline on the Baylis-Hillman acetate derived from 2-nitrobenzaldehyde, cyanogen bromide-mediated nitrile addition, and iron-acetic acid promoted reductive cyclization. This approach is also applied to the preparation of imidazol[2,1-b]quinazoline-2-ones and imidazo[2,1-b]quinazolines in one pot.

[全文传递流程]：

一般上传文献全文的时限在1个工作日内