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Highly Efficient Method for C-5 Halogenation of Pyrimidine-Based Nucleosides in Ionic Liquids

  作者 KUMAR VINEET; YAP JEREMY; MUROYAMA ANDREW; MALHOTRA SANJAY V  
  选自 期刊  Synthesis;  卷期  2009年-23;  页码  3957-3962  
  关联知识点  
 

[摘要]A novel, highly efficient, convenient, and benign methodology for C-5 halogenation of pyrimidine-based nucleosides has been developed using N-halosuccinimides as halogenating reagents without using any catalyst in ionic liquid medium. The ionic liquids were successfully recovered and reused for all the reactions.

 
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