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Synthesis of New Compounds Containing the Pyrazolo[3,4-b]pyridine-3-one Subunit

  作者 FADEL S; SUZENET F; HAFID A; RAKIB E M; KHOUILI M; PUJOL M D; GUILLAUMET G  
  选自 期刊  Journal of Heterocyclic Chemistry;  卷期  2009年46-6;  页码  1177-1184  
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[摘要]A convenient route for the synthesis of pyrazolo[3,4-b]pyridine-3-ones via condensation of 3-amino-1-phenylpyrazolin-5-one with 4-hydroxy-6-methylpyran-2-one is described. The pyrazolo[3,4-b]pyridine-3-one isomers obtained were functionalized at 1-, 4-, or 6- position by different pharmacophore entities allowing the synthesis of new compounds with promising biological activities.

 
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