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[摘要]:A convenient route for the synthesis of pyrazolo[3,4-b]pyridine-3-ones via condensation of 3-amino-1-phenylpyrazolin-5-one with 4-hydroxy-6-methylpyran-2-one is described. The pyrazolo[3,4-b]pyridine-3-one isomers obtained were functionalized at 1-, 4-, or 6- position by different pharmacophore entities allowing the synthesis of new compounds with promising biological activities. |
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