An Efficient Synthesis of Pyrido[2,3-d]pyrimidine Derivatives in Ionic Liquid

[摘要]：A series of 5,7-diarylpyrido[2,3-d]pyrimidine-2,4(1H,3H)-diones was synthesized via the reaction of 6-aminopyrimidine-2,4-dione and alpha,beta-unsaturated ketones in ionic liquid without using any catalyst. This protocol has the advantages of easier work-up, milder reaction conditions, high yields, and environmentally benign procedure over traditional methods.

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