SYNTHESIS OF HETEROARYL-FUSED PYRAZOLES AS P38 KINASE INHIBITORS
作者
ABBOT SARAH C; BILLEDEAU ROLAND J; DEWDNEY NOLAN J; GABRIEL TOBIAS; GOLDSTEIN DAVID M; MCCALEB KRISTEN L; SOTH MICHAEL; TREJOMARTIN TERESA ALEJANDRA; ZECIC HASIM
[摘要]：The synthesis of pyrazolo-pyridine, pyrimidine, pyrazine and pyridazine heterocycles is described. In addition, we report the utilization of 2,4-difluorophenoxide as a leaving group, to facilitate formation of the desired pyrazole adducts.
