PEPTIDE MASS SPECTROMETRY BY IONIC PROBE ATTACHMENT IONIZATION USING NHS-TMPYBOX AND MAL-TMPYBOX

[摘要]：The application of a new ionization method that uses metal-complex-based ionization probes containing the 2,6-bis(oxazolinyl)pyridine (pybox) ligand for bioactive peptides is presented. Bradykinin, angiotensin-I, angiotensin-I I, and nociceptine as well as a couple of pentapeptides were analyzed. This method was proven to effectively ionize large complex molecules, including biomolecules.

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