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N-PROTECTED N-2-ETHOXYMETHYLENE PHENYLGLYCINE HYDRAZIDES AS PRECURSORS OF 1,3,4-OXADIAZOLE DERIVATIVES

  作者 KUDELKO AGNIESZKA; ZIELINSKI WOJCIECH  
  选自 期刊  Heterocycles;  卷期  2010年81-4;  页码  883-896  
  关联知识点  
 

[摘要]New derivatives of N-2-ethoxymethylene phenylglycine hydrazide protected at the amino group by acetyl and tert-butoxycarbonyl were synthesized with reactions of N-protected phenylglycine hydrazides and triethyl orthoesters. They underwent cyclization to the corresponding N-protected 2-aminomethyl-1,3,4-oxadiazoles in the presence of glacial acetic acid.

 
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