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Novel Nucleophilic Heterocyclic Carbene Mediated Stereoselective Conjugate Addition of Enals to Nitrostyrenes via Homoenolate

  作者 NAIR VIJAY; SINU C R; BABU BENEESH P; VARGHESE VIMAL; JOSE ANU; SURESH ERINGATHODI  
  选自 期刊  Organic Letters;  卷期  2009年11-24;  页码  5570-5573  
  关联知识点  
 

[摘要]A stereoselective Michael addition of homoenolate, generated from enals by nucleophilic heterocyclic carbene (NHC) catalysis, to beta-nitrostyrenes is reported for the first time. The products of this reaction obtained in good yields are of potential value in the synthesis of a variety of acyclic and heterocyclic compounds.

 
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