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[摘要]:A series of spirooxindoles containing tri- and tetracyclic fused pyrrolo benzo[b]thiophene 1,1-dioxide derivatives was synthesized regioselectively via a multicomponent 1,3-dipolar cycloaddition of isatin, benzo[b]thiophene 1,1-dioxide and sarcosine or L-proline in methanol under reflux condition. Also a series of spiro frameworks having tri- and tetracyclic fused pyrrolo benzo[b]thiophene 1,1-dioxide derivatives was synthesized from ninhydrin, 11H-indeno[1,2-b]quinoxalin-11-one and acenaphthenequinone using benzo[b]thiophene 1,1-dioxide as a dipolarophile. The methodology affords high yields of products in short reaction time. |
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