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A Novel Method for the Synthesis of 2-Trifluoromethylindoles from N-(o-Haloaryl)alkynylimines

  作者 CHEN ZIXIAN; ZHU JIANGTAO; XIE HAIBO; LI SHAN; WU YONGMING; GONG YUEFA  
  选自 期刊  SYNLETT;  卷期  2010年-9;  页码  1418-1420  
  关联知识点  
 

[摘要]Treatment of various types of N-(o-haloaryl)-alkynylimines in the presence of Pd(PPh3)(2)Cl-2 gave 2-trifluoromethylindoles in high yields. This approach provides a novel and facile access to the biologically important fluorine-containing indole derivatives.

 
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