Remarkably Mild and Efficient Cetrimonium Bromide Catalyzed Friedel-Crafts Amidoalkylation of Sesamols with N-Boc Imines Generated In Situ in Aqueous Medium

[摘要]：A remarkably mild and efficient cetrimonium bromide (CTAB) catalyzed Friedel-Crafts amidoalkylation of sesamol or its 2-substituted derivatives with N-Boc imines generated in situ was developed. A wide range of 6-amidoalkyl sesamols were synthesized in high yields. This methodology was also applicable to 2-naphthols.

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