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Desulfonylation of Indoles and 7-Azaindoles Using Sodium tert-Butoxide

  作者 CHAULET CHARLOTTE; CROIX CECILE; BASSET JOAN; PUJOL MARIADOLORES; VIAUDMASSUARD MARIECLAUDE  
  选自 期刊  SYNLETT;  卷期  2010年-10;  页码  1481-1484  
  关联知识点  
 

[摘要]A mild method for the desulfonylation of N-indoles and N-azaindoles is described. Deprotection is carried out under basic conditions, using sodium tert-butoxide in dioxane. Several functionalized indoles and 7-azaindoles were efficiently deprotected by this method, which is mild enough to be used to deprotect compounds including functions that are known to be sensitive to acidic or basic conditions.

 
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