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Synthesis of a Racemic Nicotine-Lobeline Hybrid

  作者 RANAIVONDRAMBOLA TSIRESY; HATTON WILFRIED; FELPIN FRANCOISXAVIER; EVAIN MICHEL; MATHEALLAINMAT MONIQUE; LEBRETON JACQUES  
  选自 期刊  SYNLETT;  卷期  2010年-11;  页码  1631-1634  
  关联知识点  
 

[摘要]The first synthesis of a racemic nicotine-lobeline hybrid is described based on a diastereoselective allylation and an RCM reaction as key steps. This synthetic route paves the way to the preparation of original potential ligands of nAChRs.

 
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