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New complement regulator exposed

  作者 Lesher, A; Song, WC  
  选自 期刊  Blood;  卷期  2009年114-12;  页码  2363-2364  
  关联知识点  
 

[摘要]The plasma protein CFH is a critical complement regulator with relevance to human diseases. The function of several smaller, CFH-related proteins (CFHRs) has been a mystery. In this issue of Blood, Heinen and colleagues identify CFHR-1 as a novel inhibitor of C5 convertase and the terminal complement pathway.(1)

 
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