An efficient preparation of N-alkyl-2-benzazepine derivatives and investigation of their biological activity

[摘要]：N-Alkyl-2-benzazepine derivatives are readily prepared through N-alkylation of secondary 2-benzazepines that are constructed via 7-endo selective cyclization of radical cyclization of N-boc-N-(2-bromo5-methoxyphenylmethyl) methacrylamides. The structure and activity relationship of these derivatives are examined. (C) 2009 Elsevier Ltd. All rights reserved.

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