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Bronsted acid-catalyzed Nazarov cyclization of pyrrole derivatives accelerated by microwave irradiation

  作者 Bachu, P; Akiyama, T  
  选自 期刊  Bioorganic & Medicinal Chemistry Letters;  卷期  2009年19-14;  页码  3764-3766  
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[摘要]The Bronsted acid-catalyzed Nazarov cyclization of pyrrole derivatives was developed. Microwave irradiation accelerated the Nazarov cyclization significantly at 40 degrees C to give cyclopenta[b] pyrrole derivatives in excellent yields with high trans selectivity. (C) 2009 Elsevier Ltd. All rights reserved.

 
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