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4,4-Disubstituted cyclohexylamine based CCR5 chemokine receptor antagonists as anti-HIV-1 agents

  作者 Duan, MS; Aquino, C; Dorsey, GF; Ferris, R; Kazmierski, WM  
  选自 期刊  Bioorganic & Medicinal Chemistry Letters;  卷期  2009年19-17;  页码  4988-4992  
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[摘要]A series of 4,4-disubstituted cyclohexylamine based CCR5 antagonists has been designed and synthesized. Their antiviral structure-activity relationship has been extensively explored. (C) 2009 Elsevier Ltd. All rights reserved.

 
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