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Oxylipins from Dracontium loretense

  作者 Benavides, A; Napolitano, A; Bassarello, C; Carbone, V; Gazzerro, P; Malfitano, A; Saggese, P; Bifulco, M; Piacente, S; Pizza, C  
  选自 期刊  Journal of natural products;  卷期  2009年72-5;  页码  813-817  
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[摘要]Four novel oxylipins (1-4) were isolated from the n-butanol extract of the corms of Dracontium loretense. Their structures were assigned by 1D and 2D NMR analyses and electrospray ionization multistage ion trap mass spectrometry (ESI-ITMSn) data. Relative configurations were assigned on the basis of combined analysis of homonuclear and heteronuclear (2,3)J couplings, along with ROE data. Oxylipin 2 exhibited an immunostimulatory effect on human PBMC proliferation.

 
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