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Daclizumab a novel corticosteroid-sparing therapy for asthma?

  作者 Antoniu, SA  
  选自 期刊  Expert opinion on investigational drugs;  卷期  2009年18-3;  页码  369-371  
  关联知识点  
 

[摘要]Background: In asthma, inhaled corticosteroids are not always able to maintain an optimal therapeutic control despite being used at high doses; other anti-inflammatory therapies are needed. Several such therapies, including daclizumab, are currently under evaluation. Objective: To discuss the results of study on daclizumab in asthma patients. Methods: Analysis of efficacy and safety data from a randomised placebo-controlled study performed in patients with moderate to severe asthma and suboptimal control under high doses of inhaled corticosteroids. Conclusions: Daclizumab demonstrated significant efficacy and its further clinical evaluation in asthma is supported by these results.

 
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