Amiloride derived inhibitors of acid-sensing ion channel-3 (ASIC3)

[摘要]：A series of amiloride derivatives modified at the 5-position of the pyrazine ring were evaluated as inhibitors of acid-sensing ion channel-3 (ASIC3), a novel target for the treatment of chronic pain. (C) 2009 Elsevier Ltd. All rights reserved.

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