4-Phenyl-7-azaindoles as potent and selective IKK2 inhibitors

[摘要]：The synthesis and SAR of a novel series of IKK2 inhibitors are described. Modi. cation around the hinge binding region of the 7-azaindole led to a series of potent and selective inhibitors with good cellular activity. (C) 2009 Elsevier Ltd. All rights reserved.

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