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Reactions of alkylation of biologically interesting triazolo[4,5-g]quinolines and triazolo[4,5-g]quinoline-1-oxides with electrophilic reagents.

  作者 Carta, Antonio;Sias, Angela;Piras, Sandra;Paglietti, Giuseppe;  
  选自 期刊  Heterocycles;  卷期  2008年75-10;  页码  2493-2505  
  关联知识点  
 

[摘要]With the aim to improve the biol. activities discovered for compds. contg. the triazolo[4,5-g]quinoline nucleus, 4-chlorotriazolo[4,5-g]quinolines and some its triazolo-N1-oxide derivs. were alkylated with electrophilic reagents. Both mixts. of N1,2,3-alkyl isomers and selectively N1-O-alkyl derivs, e.g., I (R1 = H, OH, Et; R2 = Me, Et, CH2CNCH2Ph, 4-NO2PhCH2) were obtained and discussed (no biol. tests or results shown).

 
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