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A convenient one-pot three component approach to synthesis of highly substituted iminothiazolines.

  作者 Samimi, Heshmat Allah;Mamaghani, Manouchehr;Tabatabaeian, Khalil;  
  选自 期刊  Heterocycles;  卷期  2008年75-11;  页码  2825-2833  
  关联知识点  
 

[摘要]An efficient one-pot three component method was developed for the synthesis of highly substituted 2-iminothiazolines by the reaction of isothiocyanates, primary amines and a-bromoketones in ambient temp. The reaction produced the desired products in a completely regioselective manner in excellent yields (78-94%).

 
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