[摘要]：From the ocean: Ammosamides A (1) and B (2) were isolated from a marine-derived Streptomyces species collected in the Bahamas. The structures of these chlorinated tricyclic pyrroloquinoline alkaloids were solved using X-ray crystallog. techniques. Ammosamide A (1) was shown to contain an unusual thio-g-lactam ring. Both metabolites show specific nanomolar cytotoxicity against selected cancer cell lines.
