In Situ "Click" Assembly of Small Molecule Matrix Metalloprotease Inhibitors Containing Zinc-Chelating Groups.

[摘要]：A panel of small mol.-based MMP inhibitors contg. rhodanine warheads was assembled using "one-pot" click chem. Upon biol. screening, moderate inhibitors were identified which specifically target MMP-7 and MMP-13 over other MMPs.

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