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Probing the lactose譍M3 carbohydrate-carbohydrate interaction with glycodendrimers.

  作者 Seah, Nicole;Santacroce, Paul V.;Basu, Amit;  
  选自 期刊  Organic Letters;  卷期  2009年11-3;  页码  559-562  
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[摘要]Multivalent glycoconjugates were prepd. using generation-4 PAMAM dendrimers, and their interaction with Langmuir monolayers contg. GM3 was investigated. Excessive carbohydrate valency adversely affects the carbohydrate-carbohydrate interaction. The GM3 monolayer selectively interacts with lactose-functionalized dendrimers in the presence of calcium ions.

 
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