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Glycosylated asterisks are among the most potent low valency inducers of Concanavalin A aggregation.

  作者 Sleiman, Mazen;Varrot, Annabelle;Raimundo, Jean-Manuel;Gingras, Marc;Goekjian, Peter G.;  
  选自 期刊  Chemical Communications;  卷期  2008年-48;  页码  6507-6509  
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[摘要]A new class of sulfurated, semi-rigid, radial and low-valent glycosylated asterisk ligands with potential dual function as ligand and probe has some of the highest inhibition potencies of Con A-induced hemagglutination, by using a crosslinking mechanism of Con A which amplifies the enhancement to near nanomolar concns. with the a-d-mannose asterisk.

 
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