[摘要]：Tetralactam macrocycles can be functionalized by a variety of cross-coupling reactions. A modular toolbox strategy is presented that allows (1) several tetralactam macrocycles to be covalently connected with each other or with a central spacer, (2) the macrocycles to be substituted with or connected to different chromophores, and (3) metal-coordination sites to be attached to the macrocycles. With this approach different oligo-macrocyclic hosts were obtained with great structural diversity and enormous potential for further functionalization. Rotaxanes made from these macrocycles were synthesized to demonstrate their utility in building more complex supramol. architectures.
