[摘要]：This communication describes the deproto-metalation of a large range of aroms. including heterocycles using a newly developed lithium-cadmium base; the reaction proceeds at room temp. with an excellent chemoselectivity and efficiency, and proved to be regioselective in most cases. Thus, treatment of PhOMe with CdCl2譚MEDA/LiTMP in THF at room temp. followed by quenching with I2 gave 74% 2-IC6H4OMe.
