[摘要]:We observed the glucose concentration of solutions using a near-field microwave microprobe (NFMM). Instead of the usual technique, we take advantage of the noncontact and label-free evaluation capabilities of a NFMM. A NFMM with a high Q dielectric resonator allows observation of small variations of the relative permittivity due to changes in the glucose concentration. By measuring the reflection coefficient S-11 at an operating frequency near 4.5 GHz, we could observe the concentration of glucose with a detectable resolution of 0.5 mg/ml (0.05%). A glucose biosensor using a NFMM provides a unique approach to monitor glucose concentration. (C) 2008 Elsevier B.V. All rights reserved.