Indium-Copper and Indium-Silver Mediated Barbier-Grignard-Type Alkylation Reaction of Aldehydes Using Unactivated Alkyl Halides in Water.

[摘要]：An efficient method has been developed for the Barbier-Grignard-type alkylation reaction of aldehydes (including aliph. version) using unactivated alkyl halides in water in the presence of an In/CuI/I2 or In/AgI/I2 system. The reactions proceeded more efficiently in water than in org. solvent. In, CuI or AgI, and I2 were all essential for the efficient progress of the reactions. A radical-type reaction mechanism was studied and proposed by using 4-pentenal as substrate.

[全文传递流程]：

一般上传文献全文的时限在1个工作日内