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Scalable Preparation of Both Enantiomers of 2-(1-Hydroxy-2-oxocyclohexyl)acetic Acid.

  作者 Vamos, Mitchell;Kobayashi, Yoshihisa;  
  选自 期刊  Journal of Organic Chemistry;  卷期  2008年73-10;  页码  3938-3941  
  关联知识点  
 

[摘要]The efficient, scalable prepn. of both enantiomers of 2-(1-hydroxy-2-oxocyclohexyl)acetic acid in enantiomerically pure form for the (S)-isomer and in 27% (7 steps) for the (R)-isomer from cyclohexanone is reported.

 
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