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Methimazole-Based Ionic Liquids.

  作者 Siriwardana, Amal I.;Crossley, Ian R.;Torriero, Angel A. J.;Burgar, Iko M.;Dunlop, Noel F.;Bond, Alan M.;Deacon, Glen B.;MacFarlane, Douglas R.;  
  选自 期刊  Journal of Organic Chemistry;  卷期  2008年73-12;  页码  4676-4679  
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[摘要](Heterocyclic Compounds (More Than One Hetero Atom)) Section The alkylation reaction of methimazole (2-mercapto-1-methylimidazole) with iodoethane and 1-chlorobutane produced the corresponding S-alkylmethimazole halides which were subjected to anion metathesis with two different metal salts (MA) to afford methimazole-based room-temp. ionic liqs. in 82-87% yields. The formation of S-alkylated products suggests that methimazole reacts through the thione tautomer.

 
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