[摘要]：A tetra-azido calix[4]arene deriv. was allowed to Cu(I)-catalyzed azide-alkyne cycloaddn. (CuAAC) (click reaction) with ethynyl tetra-O-benzyl-C-galactoside in the presence of CuI and i-Pr2EtN in three different ionic liqs. Reactions were performed at 80 癈 by thermal and MW dielec. heating. In all cases, multiple cycloaddns. took place to give a triazole-linked tetra-C-galactosyl-calix[4]arene in up to 90% yield. The [C8dabco][N(CN)2] ionic liq. was also used to perform the multi-click reactions with propargyl O-lactoside and S-sialoside.
