Effects of phenolic componnds isolated from Rabdosia japonica on B16-F10 melanoma cells

[摘要]：Pedalitin isolated from the aerial part of Rabdosia japonica (Labiatae), exhibited cytotoxicity against the murine B16-F10 melanoma cell line with an IC50 of 30 gm (9.5 mu g/mL). As the cells were cultured with this flavone, melanin production was not suppressed, but rather enhanced. Quercetin isolated from the same source exhibited similar activities, but rutin showed neither activity. Copyright (c) 2008 John Wiley & Sons, Ltd.

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