Intramolecular Friedel-Crafts reaction of indoles with carbonyl groups: a simple synthesis of 3- and 4-substituted b-carbolin-1-ones.
[摘要]:The intramol. Friedel-Crafts reaction of indole-2-carboxylic acid b-oxoamides catalyzed by trifluoroacetic acid or InCl3, is a convenient method for the synthesis of 3-aryl-, 4-aryl-, and 4-alkyl-b-carbolin-1-ones.
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