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Synthesis of new pyrrolobenzazepines via Pictet-Spengler cyclization.

  作者 Gracia, Stephanie;Schulz, Jurgen;Pellet-Rostaing, Stephane;Lemaire, Marc;  
  选自 期刊  SYNLETT;  卷期  2008年-12;  页码  1852-1856  
  关联知识点  
 

[摘要]A new 6-step divergent strategy was developed allowing access to pyrrolobenzazepine structures from pyrrole. This strategy was based on a regioselective Friedel-Crafts acylation followed by a Pictet-Spengler cyclization.

 
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