个性化文献订阅>期刊> Organic Letters
 

Regio- and Chemoselective Multiple Functionalization of Pyrimidine Derivatives by Selective Magnesiations using TMPMgCl譒iCl.

  作者 Mosrin, Marc;Knochel, Paul;  
  选自 期刊  Organic Letters;  卷期  2008年10-12;  页码  2497-2500  
  关联知识点  
 

[摘要]Successive regio- and chemoselective magnesiations of pyrimidines using TMPMgCl譒iCl furnish, after trapping with various electrophiles, highly functionalized derivs., e.g. I, in good to excellent yields. Applications to the synthesis of antiviral and anti-inflammatory agents such as p38 and sPLA2 kinase inhibitors are reported.

 
      被申请数(0)  
 

[全文传递流程]

一般上传文献全文的时限在1个工作日内